13 Jun 2015

Texting for CPR Feasible in Out-of-Hospital Cardiac Arrest (CME/CE)

(MedPage Today) -- City's EMS system to alert nearby trained laypersons raised rates of early CPR
16 Jan 2015

Gold Nanoparticle Test Strip to Detect Heart Attacks

Increased levels of the protein troponin in a patient’s blood is a marker for a cardiac infarction that may have recently occurred. Researchers at NYU Polytechnic School of Engineering have reported in journal Plasma Processes and Polymers on the development of new test strips that use gold nanoparticles to detect troponin I (cTn-I) with high sensitivity, potentially leading to a fast and...
18 Dec 2014

CDC's 10 most important public health challenges of 2014

In a year that has been fraught with public health crises, the CDC has had more than its share of important work to do. While 2014’s Ebola epidemic dominated international headlines, the response to this crisis was only one mission the CDC undertook during the past year. “CDC’s Ebola response is the largest global effort in the agency’s history, but we’re carrying out many other public health...
22 Oct 2014

NT-proBNP levels improved CVD risk prediction in women

N-terminal pro–B-type natriuretic peptide modestly improved measures of CVD risk prediction in women with numerous CV events, according to new data published in the Journal of the American College of Cardiology.The addition of NT-proBNP levels to traditional risk factors and Reynolds Risk Score covariables also led to a small but significant improvement in CVD risk prediction.
30 Aug 2014

Highly Sensitive cTnT Safely Rules Out MI in One Hour

A highly sensitive assay for cardiac troponin T has the ability to safely and effectively rule-out/rule-in acute MI within one hour in patients presenting to the emergency department with chest... For complete story visit
12 Aug 2014

Reviews address challenges of interpreting troponin levels in patients with chronic kidney disease

Two reviews being published in Annals of Internal Medicine address the challenges associated with using troponin levels to diagnose cardiac disease in patients with chronic kidney disease (CKD).
06 May 2014

Blood Test Predicts Heart Attack Risk

High-sensitivity cardiac troponin T is a relatively new biomarker used in the diagnosis of heart attack and is detectable in...
14 Apr 2014

Cardiovascular biomarker market could hit $7.2B by 2018

The global market for diagnostic biomarkers detecting cardiovascular disease is expected to soar steadily at a compound annual growth rate of 12.8 percent between 2013 and 2018.
30 Mar 2014

High-sensitivity cardiac troponin T predicted patients with chest pain at minimal risk

WASHINGTON — Patients presenting to the ED with an undetectable level of high-sensitivity cardiac troponin T and whose electrocardiogram shows no sign of ischemia have a minimal risk for MI or death within 30 days and can be safely discharged, according to research presented here.In a study of 14,636 patients (mean age, 47 years; 53% women) who reported to a Swedish ED with chest pain from 2010...
28 Jan 2014

Prognostic Performance of High-Sensitivity Cardiac Troponin Assay Evaluated

Cardiac troponin is the preferred biomarker for diagnosis of acute myocardial infarction and is useful for risk stratification of patients...
07 Jan 2014

Novel Approach Predicts Outcomes in Heart Failure Patients

A new method has been identified that determines whether a patient's heart will fail, which in the future may help...
20 Dec 2013

Heart disease remains No. 1 cause of death in US

Heart disease remains the No. 1 cause of death in United States and stroke remains the No. 4 cause of death, according to the American Heart Association’s Heart Disease and Stroke Statistical Update 2014.Nearly 380,000 deaths each year are attributed to heart disease and more than 129,000 deaths to stroke, according to a press release.
12 Nov 2013

PET/CT: C-reactive protein could be a precursor to cardiovascular disease

FDG uptake rose substantially in PET/CT scans of patients with higher levels of C-reative protein in their carotid arteries, pinpointing a potential biomarker for cardiovascular disease, according to an article published online Oct. 31 in the Journal of Nuclear Medicine.
06 Nov 2013

Biomarker Can Predict Events in Afib Patients (CME/CE)

(MedPage Today) -- Beta-trace protein, a biomarker that has been associated with both kidney damage and an increased cardiovascular risk, may help identify high-risk atrial fibrillation patients, researchers found.
02 Oct 2013

Point-of-Care Device Compared for Cardiac Troponin Assay

A fingerstick point-of-care testing for cardiac troponin I has been compared to conventional venipuncture POC testing.
03 Sep 2013

BIC-8: Negative troponin and copeptin tests rule out acute coronary syndrome

A negative troponin test and a negative copeptin test can safely rule out acute coronary syndrome, according to the results of a new study. For complete story visit
10 Jun 2013

HyTest anti-cTnI antibodies utilized in a novel, highly sensitive cTnI assay

LamdaGen’s Optical Enhancement System™ (OES™) based diagnostic platform allows precise quantification of cTnI in human whole blood, plasma and serum samples. For optimization of the cTnI assay, the company utilized HyTest’s monoclonal antibodies and troponin I-T-C complex. For more information, please see the application note below. Download Application Note
09 Apr 2013

New Troponin T Test Predictive in Stable CAD (CME/CE)

(MedPage Today) -- In patients with stable coronary artery disease, higher levels of high-sensitivity cardiac troponin T independently predicted poorer outcomes, researchers found.
15 Feb 2013

Cardiac troponin I a prognostic marker in stable coronary disease

In this new analysis of the PEACE trial, increases in cTnI, detected using a highly sensitive assay, were associated with 88% higher risk of cardiovascular death or heart failure and a 44% increased... For complete story visit
14 Feb 2013

CV risk in diabetics climbs with small, silent troponin elevations

It can be useful to see diabetes as a CAD risk-equivalent, but CV risk isn't equivalent in all diabetics. Are troponins a key to stratifying them for CV risk or guiding CV therapy? For complete story visit
14 Feb 2013

Troponin I Predicts Event Risk in CAD (CME/CE)

(MedPage Today) -- In patients with stable coronary artery disease, troponin I levels measured with a high-sensitivity assay add prognostic information to conventional risk markers and troponin T levels, researchers found.
05 Feb 2013

Novel Immunoassay Evaluated for Cardiac Troponin

The analytical performance of an immunoenzymometric assay for the cardiac troponin has been appraised and compared with other...
16 Jan 2013

Precise Troponin Test Could Cut SPECT Use in ED

A high-sensitivity troponin T (hsTnT) test correlated well with abnormal cardiac SPECT scans, potentially allowing for less use of costly imaging for emergency chest pain patients, researchers suggested.
02 Jan 2013

Renal Failure Hikes Mortality with LVADs (CME/CE)

(MedPage Today) -- Among patients receiving a left ventricular assist device (LVAD) for end-stage heart failure, developing acute renal failure after implantation predicted a lower likelihood of surviving the next year, a single-center study showed.
14 Nov 2012

Panel Lays Out Blueprint for Troponin Testing

Highly sensitive troponin assays have made it necessary for professional societies to issue the first-ever consensus statement on troponin testing.
18 Sep 2012

Troponin May Be Tx Guide in Non-STEMI ACS

Although aggressive treatment showed a small, nonsignificant benefit over conservative management in most elderly patients with non-ST-segment elevation acute coronary syndrome, it helped a subgroup with elevated troponin significantly, researchers reported.
10 Sep 2012

Idenix measuring the levels of ultra-sensitive troponin

To address the FDA's concerns, Idenix has EKGs on its patients and is running echocardiograms on them. It also is measuring the levels of ultra-sensitive troponin, a measure of cell injury to pick up cardiomyopathy, and pro-brain natriuretic peptide to look at early heart failure. To date, all the assays that Idenix has looked at have been normal. Read Full Article
14 Aug 2012

Troponin algorithm rules MI in or out in 77% of chest-pain patients

More details have been published about a simple algorithm that researchers say can rule in or rule out acute MI in almost 80% of chest pain patients presenting to the emergency room. For complete story visit
10 Aug 2012

Scientists at University of Pittsburgh Medical Center Release New Data on Cardiology

Skeletal muscle derived stem cells (MDSCs) transplanted into injured myocardium can differentiate into fast skeletal muscle specific myosin heavy chain (sk-fMHC) and cardiac specific troponin-I (cTn-I) positive cells sustaining recipient myocardial function. Read Full Article
04 Jul 2012

Serum Tubes Reduce False Positive Troponin Results

Blood samples collected in both Rapid Serum Tubes and Plasma Separator Tubes have been compared for cardiac troponin analysis.
11 Jun 2012

Troponin T Blood Levels Identify Risk of Death Following Surgery

A simple blood test can help identify people who are at high risk of dying within the month after noncardiac...
18 Apr 2012

World Congress of Cardiology (WCC) Scientific Sessions 2012

Read clinically focused news coverage of key developments from the meeting. Medscape Cardiology
29 Mar 2012

Elevated glucose associated with undetected heart damage

A new study led by researchers at the Johns Hopkins Bloomberg School of Public Health suggests that hyperglycemia (high blood sugar) injures the heart, even in patients without a history of heart disease or diabetes. Researchers found that elevated levels of glycated hemoglobin (HbA1c), a marker for chronic hyperglycemia and diabetes, were associated with minute levels of the protein troponin T (...
05 Mar 2012

New call to redefine troponin threshold for periprocedural MI

Another study suggests that the currently recommended troponin cutoff for diagnosing periprocedural MI is overly sensitive and identifies too many people as having had such an event. A stricter... For complete story visit
24 Feb 2012

Cardiovascular Disease Prevention Guidelines - Benchmarking Study Triggers Rethink

The 2012 Joint European CVD Prevention Guidelines , that will be published at the EuroPRevent 2012 later this year, will be more concise, compact and supported by fewer references, according to Professor Joep Perk, Chairperson of the Task Force of the fifth edition, who states that the aim is to provide guidelines that contain recommendations, which can be readily applied and t...
05 Jan 2012

Biomarker Tests Could Significantly Speed Up Heart Attack Diagnosis

According to a study in the December issue of JAMA, using a contemporary or highly sensitive test for levels of the biomarker troponin I, a protein in the muscle tissue, in patients admitted to emergency departments with chest pain, could potentially assist in ruling out a diagnosis of a heart attack...
06 Dec 2011

Troponin's Role in Heart Failure Uncertain (CME/CE)

(MedPage Today) -- Assays that enable the measurement of minute levels of troponin T show that temporal changes in circulating levels of the enzyme are associated with worsening heart failure but are of limited prognostic value, according to an analysis of two randomized clinical trials.
17 Nov 2011

Blood Test for Cardiac Protein Diagnoses Heart Attack

A novel blood test for a cardiac biomarker has been used to determine whether a patient has had a heart...
18 Oct 2011

Biomarker Levels May Be Key to Heart Failure Decline (CME/CE, with audio)

(MedPage Today) -- Monitoring levels of amino-terminal pro–B-type natriuretic peptide (NT-proBNP) and keeping them below a certain threshold proved to be more beneficial for heart failure patients than the standard of care, a single-center study found.
13 Oct 2011

Increasing Cardiovascular Disease In China, Urgent Need For Prevention

At over 40%, the mortality rate due to cardiovascular disease (CVD) in China is amongst the highest in the world¹ and has been rightly described as an epidemic. Its population faces a catalogue of CVD risk factor statistics that expose high levels of obesity, diabetes, cholesterol and blood pressure, and a smoking habit within males that is proving stubborn to address...
28 Sep 2011

Troponin detected with myopathy can lead to false-positive coronary diagnosis

Mayo Clinic scientists have demonstrated—for the first time—that patients with skeletal-muscle disease can register "false-positive" troponin tests, giving the impression they have suffered... For complete story visit
20 Sep 2011

Troponin changes in elderly reflect physical-activity levels, predict HF risk

Could high-sensitivity troponin-T levels help track the success of exercise programs for CV-disease prevention or even exercise-based interventions for existing disease? For complete story visit
10 Jun 2011

Cardiac Biomarker ST2 Predicts Outcomes In Ambulatory Heart Failure Patients

The novel cardiac biomarker ST2 was highlighted in a presentation at last month's 2011 Heart Failure Congress of the European Society of Cardiology in Gothenburg, Sweden. As this study and others have demonstrated, a patient's ST2 level can help a physician better predict prognosis in ambulatory, chronic heart failure patients, which can allow physicians to more appropriately tailor care...
10 May 2011

News From The Journal Of Clinical Investigation: May 9, 2011

VIROLOGY: Stability critical to immune-stimulating capacity Key to the success of vaccines that provide protection from infection with viruses is their ability to stimulate immune cells known as CD8+ T cells...
06 May 2011

The American Heart Association And The Society Of Chest Pain Centers Join Forces To Reduce Death From Heart Disease

The Society of Chest Pain Centers (SCPC), an international organization committed to the elimination of heart disease as the number one cause of death, and The American Heart Association a national organization dedicated to the prevention of cardiovascular diseases and stroke, today announced they will be joining efforts to save even more lives...
05 May 2011

Rapid Blood Test Detects Damaged Cardiac Muscle

A microwave-accelerated and metal-enhanced fluorescence technique was used to detect the protein troponin I, a specific indicator of...

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